Molsketch

• Tested by running it
• Seen in the app
• The manual says yes
• Partly, with the reason shown
• Not supported
• Not established, which is not the same as no

Select a mark for its proof. A filled mark opens our screenshot, or the manual if the check left nothing to picture. A ring opens the manual.

Drawing structures

• Yes, tested by running it: Single, double, and triple bonds drawn; features-test.png. Opens the screenshot.Single, double and triple bondsSingle, double, and triple bonds drawn; features-test.png.github.com
• Yes, tested by running it: Wedge, hash, and wavy bonds drawn; features-test.png. Opens the screenshot.Wedge, hash and wavy bondsWedge, hash, and wavy bonds drawn; features-test.png.github.com
• Partly: Dotted/dashed dative styles; no additional specialist bond category in controls. Opens the cited page.Dative, hydrogen and quadruple bondsDotted/dashed dative styles; no additional specialist bond category in controls.github.com
• Yes, according to the manual: Symmetric, asymmetric, and inverted asymmetric double bonds. Opens the cited page.Choose double-bond sideSymmetric, asymmetric, and inverted asymmetric double bonds.github.com
• Partly: Triangle drawn; other ring sizes and aromatic options untested. Opens the screenshot.Ring toolsTriangle drawn; other ring sizes and aromatic options untested.github.com
• Not establishedChair and Haworth rings
• Not establishedChain tool
• No: Library refresh remained empty; interface requests user-defined library folders. Opens the cited page.Template libraryLibrary refresh remained empty; interface requests user-defined library folders.sourceforge.net
• Yes, according to the manual: Save molecules as MSM files for reuse in folder-based libraries. Opens the cited page.Save your own templatesSave molecules as MSM files for reuse in folder-based libraries.github.com
• Partly: Labels supported; chemical abbreviation handling remains a TODO. Opens the cited page.Group abbreviationsLabels supported; chemical abbreviation handling remains a TODO.github.com
• Partly: Charges and custom labels; no dedicated isotope field. Opens the cited page.Charges, isotopes and atom labelsCharges and custom labels; no dedicated isotope field.github.com
• Yes, according to the manual. Opens the cited page.Radicals and lone pairsgithub.com
• Not establishedKeyboard drawing
• Partly: Rectangular selection and rotation; full free-selection transforms are not provided. Opens the cited page.Lasso select and transformsRectangular selection and rotation; full free-selection transforms are not provided.github.com
• Not establishedTilt drawings in perspective

Reactions and mechanisms

• Partly: Forward arrow drawn; alternate arrow styles not exercised. Opens the screenshot.Reaction arrowsForward arrow drawn; alternate arrow styles not exercised.github.com
• Yes, tested by running it: Curved full-head arrow drawn and exported. Opens the screenshot.Curved mechanism arrowsCurved full-head arrow drawn and exported.github.com
• Not establishedMachine-readable reactions
• Not establishedAtom mapping
• Not establishedOrbitals and symbols

Figures and layout

• Yes, according to the manual: Paste formatted text from another application. Opens the cited page.Rich text captionsPaste formatted text from another application.sourceforge.net
• Yes, according to the manual: Rectangular and rounded frames, square and curly brackets. Opens the cited page.Shapes, brackets and curvesRectangular and rounded frames, square and curly brackets.github.com
• Yes, according to the manual. Opens the cited page.Align and distributegithub.com
• Not establishedGroup and ungroup
• Yes, according to the manual: Requires the Open Babel adapter and gen2D operation. Opens the cited page.2D structure cleanupRequires the Open Babel adapter and gen2D operation.github.com
• Not establishedJournal drawing styles
• Yes, according to the manual: Bond and font preferences persist for reuse. Opens the cited page.Reusable custom stylesBond and font preferences persist for reuse.github.com
• Yes, according to the manual. Opens the cited page.Color controlgithub.com
• Partly: Blue selection outlines highlight atoms and bonds; exports clear selection. Opens the cited page.Color highlightingBlue selection outlines highlight atoms and bonds; exports clear selection.github.com
• Partly: Print preview offers page setup; multipage editing not verified. Opens the cited page.Page layout and multipagePrint preview offers page setup; multipage editing not verified.
• Not establishedImported pictures
• Not establishedTLC plates and tables

Chemistry intelligence

• Not establishedStructure checking
• Not establishedR/S and E/Z labels
• Partly: Selection displayed C47H51NO14; no mass readout found. Opens the cited page.Formula and massSelection displayed C47H51NO14; no mass readout found.github.com
• Not establishedProperty estimates
• No: Caffeine Wikidata query failed with network error 499. Opens the cited page.Name to structureCaffeine Wikidata query failed with network error 499.github.com
• No: Only editable Name field; no naming command found. Opens the cited page.Structure to nameOnly editable Name field; no naming command found.
• Not establishedNMR prediction
• Not establishedR-groups and query structures
• Not establishedPolymers and repeat units
• Not establishedPeptides and nucleic acids
• Not establishedImage to structure
• No: Caffeine Wikidata query failed with network error 499. Opens the cited page.Online structure lookupCaffeine Wikidata query failed with network error 499.github.com
• No: No 3D command in File, Edit, View, or Help. Opens the cited page.3D model viewNo 3D command in File, Edit, View, or Help.
• Partly: Open Babel imports atoms/bonds; crystal unit-cell information is discarded. Opens the cited page.Crystal structuresOpen Babel imports atoms/bonds; crystal unit-cell information is discarded.github.com

Files and exchange

• Partly: Export re-imported; reaction and mechanism arrows absent from CDXML. Opens the cited page.CDXML import and exportExport re-imported; reaction and mechanism arrows absent from CDXML.openbabel.org
• Partly: CDX import listed; no CDX save format listed. Opens the cited page.CDX import and exportCDX import listed; no CDX save format listed.
• Yes, tested by running it: Caffeine MOL opened and saved; SDF listed in formats. Opens the cited page.MOL and SDFCaffeine MOL opened and saved; SDF listed in formats.github.com
• Partly: Imported both fixtures; paclitaxel round-trip altered stereochemistry. Opens the cited page.SMILESImported both fixtures; paclitaxel round-trip altered stereochemistry.github.com
• Yes, according to the manual: Requires Open Babel's InChI support. Opens the cited page.InChIRequires Open Babel's InChI support.github.com
• Partly: Open Babel 3 imports components; reaction roles and mapping are discarded. Opens the cited page.RXN filesOpen Babel 3 imports components; reaction roles and mapping are discarded.github.com
• Yes, tested by running it: Native SVG export wrote features-test.svg. Opens the cited page.SVG exportNative SVG export wrote features-test.svg.github.com
• Yes, tested by running it: Saved through Print Preview and macOS PDF save. Opens the cited page.PDF exportSaved through Print Preview and macOS PDF save.github.com
• Partly: Default 10× scaling; 1850×1750 caffeine PNG; no DPI control. Opens the screenshot.High-resolution PNGDefault 10× scaling; 1850×1750 caffeine PNG; no DPI control.github.com
• Not establishedPaste to and from ChemDraw
• Not establishedEditable in Word or PowerPoint
• Not establishedWindows Office OLE

APIs and automation

• Not establishedPython API
• Not establishedJavaScript or TypeScript API
• Not establishedCommand-line tool
• Not establishedAI agent control
• Not establishedBuilt-in AI assistant

Embedding and extension

• Not establishedPlugins
• Partly: GPL-2.0-or-later; Qt/C++ integration undocumented. Opens the cited page.Embed in your own appGPL-2.0-or-later; Qt/C++ integration undocumented.github.com