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AI agent control
An MCP server or documented agent interface.
15 tools have this, 2 of them shown here. 0 do not. 113 not established.
- Tested by running it
- Seen in the app
- The manual says yes
- Partly, with the reason shown
- Not supported
- Not established, which is not the same as no
Select a mark for its proof. A filled mark opens our screenshot, or the manual if the check left nothing to picture. A ring opens the manual.

Yes, according to the manual: Separate AI-assistants add-on required. Reactio Draw
1.10
Info panel describes a separate AI assistants add-on and commands.

Yes, according to the manual: Separate MCP service; editor transfer requires manual SMILES/MOL import. FreeChemDraw
3.18.0
FreeChemDraw MCP card and Explore MCP Tools link.
Available, no screenshot
- Yes, according to the manual: Experimental stdio MCP; structure-level editing, no live GUI attachment. Opens the cited page.ReShikiExperimental stdio MCP; structure-level editing, no live GUI attachment.Source
- Yes, according to the manual: Hosted MCP creates, edits, converts, and exports; free account required. Opens the cited page.MolDrawFree accountHosted MCP creates, edits, converts, and exports; free account required.Source
- Yes, according to the manual: Local stdio MCP server; requires a source checkout. Opens the cited page.ChemDraftLocal stdio MCP server; requires a source checkout.Source
- Yes, according to the manual: Documented MCP server reads and writes offline .ctt project files. Opens the cited page.ChemThisTryDocumented MCP server reads and writes offline .ctt project files.Source
- Yes, according to the manual: MCP tools and REST edit the shared document. Opens the cited page.vibe-sketcherMCP tools and REST edit the shared document.Source
- Yes, according to the manual: Streamable HTTP MCP interface provides drawing, editing and analysis tools. Opens the cited page.MolChartStreamable HTTP MCP interface provides drawing, editing and analysis tools.Source
- Yes, according to the manual: Requires MCP Server plugin; controls the running editor. Opens the cited page.MoleditPyRequires MCP Server plugin; controls the running editor.Source
- Yes, according to the manual: Documented agent CLI accepts structured JSON composition and patch requests. Opens the cited page.ChemvasDocumented agent CLI accepts structured JSON composition and patch requests.Source
- Yes, according to the manual: Documented agent CLI with selectors, bundles, transactions, and JSONL sessions. Opens the cited page.ChemSemaDocumented agent CLI with selectors, bundles, transactions, and JSONL sessions.Source
- Yes, according to the manual: Documented JSON editing operations shared with agents. Opens the cited page.Structura (chem-structura)Documented JSON editing operations shared with agents.Source
- Yes, according to the manual: Documented HTTP and JSON-lines operation interface for external agents. Opens the cited page.ChemifreeDocumented HTTP and JSON-lines operation interface for external agents.Source
- Yes, according to the manual: Pro; MCP server supports figure editing; vendor claim. Opens the cited page.LabCanvas Figure Editor / MolDrawLabCanvas ProPro; MCP server supports figure editing; vendor claim.Source
- Yes, according to the manual: macOS bundled MCP helper supports repository search, modification, and export. Opens the cited page.AtomLensmacOS bundled MCP helper supports repository search, modification, and export.Source
Not established (113)
ChemDraw, Penzene, Octet Draw, SketchIQ, Covalent, ChemEdit, Chem Illustrator, Chematic Draw, Molecule Lab (The Freshman Mole), ErezDraw, MolCanvas, Kendraw, BoltzDraw, Chemliora, Molbrett, Zeanium Molecule Drawer, Sciformation VectorMol, BondForge, ChemDoodle Web Components, Chemeditor (Chemrise), ChemCanvas, MolView.com, Ketcher, AI Chemical Drawing (CubicZnS), OpenReactions, PyChem-Pro, chemfig, Molecule Builder (OvOHongYu), KetchDraw, Schrödinger Sketcher, Molsketch, Chemable, WaveSpeed AI Chemical Structure Drawer, cDraw, BondCraft, JChemPaint, Molsoft HTML5 Molecule Editor, Molecule Clipboard, MolGLideX, SketchScape, OpenChemLib JS editor, MolSketch, Dotmatics Elemental / Elemental Draw, SketchEl 2, Kekule.js, XDrawChem, SketchEl, JSME Molecule Editor, RadSketch, Ketcherails (ketcher-rails), Butlerov, schematic, ChemMD, WebMolKit, rdEditor, ChemCanvasJS, Chemical Structure Editor (CSE), Kemia, JMolDraw, MolTouch, Chemeditor (Chemie-Lernprogramme), SketChem, vue-chemdraw (0chem), ChemWriter, MCDL Java Chemical Structure Editor, Glass, molsketch-cljs, MolPad, BKChem Python 3 Modernized, ChemDoodle 2D, Marvin Desktop Suite / MarvinSketch, ChemDraft (元素智研), InDraw, Marvin JS, BKChem, BIOVIA Draw, ChemWindow (KnowItAll ChemWindow Edition), Chemistry Draw, Zoho ChemStudio, GChemPaint, KingDraw, ChemPencil, ACD/ChemSketch, Ferrum Chemical Forge, Marvin Cloud, Chem4Word, Chemtool, Lhendraw, JSDraw, ChemCAD, MoleculeSketch, FX ChemStruct / FX Draw Chemical Structures, Chemistry 4-D Draw, ChemStitch, BondDraw, ChemGraphic 2, EasyChem, MolSketchGo, MyChemise, CyBy-Draw, Elk_Draw RDKit, Chem+ Molecular Structure Editor, MolPrime+, MolGenDraw, Chirys Draw, ChemScribble, Chem Sketcher (Non_REM.Persona Laboratory), Structo, Chemograph Plus, alvaSketcher, moled, ChemWorks, Molecule