Chematic Draw

• Tested by running it
• Seen in the app
• The manual says yes
• Partly, with the reason shown
• Not supported
• Not established, which is not the same as no

Select a mark for its proof. A filled mark opens our screenshot, or the manual if the check left nothing to picture. A ring opens the manual.

Drawing structures

• Yes, tested by running it: Keyboard added nitrogen bonded to carbon; templates contained multiple bonds. Opens the screenshot.Single, double and triple bondsKeyboard added nitrogen bonded to carbon; templates contained multiple bonds.github.com
• Partly: Wedge tool selected; stereochemical SMILES exported without stereo. Opens the cited page.Wedge, hash and wavy bondsWedge tool selected; stereochemical SMILES exported without stereo.github.com
• No: Accepted bond orders are single, double, triple and aromatic. Opens the cited page.Dative, hydrogen and quadruple bondsAccepted bond orders are single, double, triple and aromatic.github.com
• No: Double bonds are always centered. Opens the cited page.Choose double-bond sideDouble bonds are always centered.github.com
• Yes, tested by running it: Benzene template inserted a six-membered ring. Opens the screenshot.Ring toolsBenzene template inserted a six-membered ring.github.com
• Not establishedChair and Haworth rings
• Not establishedChain tool
• Yes, tested by running it: Inserted benzene from Templates panel. Opens the cited page.Template libraryInserted benzene from Templates panel.github.com
• Not establishedSave your own templates
• Not establishedGroup abbreviations
• Yes, tested by running it: Keyboard added a nitrogen atom. Opens the screenshot.Charges, isotopes and atom labelsKeyboard added a nitrogen atom.github.com
• Not establishedRadicals and lone pairs
• Yes, tested by running it: Shift+N added a bonded atom. Opens the cited page.Keyboard drawingShift+N added a bonded atom.github.com
• Partly: Rectangular selection, rotation and flips; no resize transform. Opens the cited page.Lasso select and transformsRectangular selection, rotation and flips; no resize transform.github.com
• Not establishedTilt drawings in perspective

Reactions and mechanisms

• Partly: Selected arrow tool; canvas click did not place an arrow. Opens the cited page.Reaction arrowsSelected arrow tool; canvas click did not place an arrow.github.com
• Partly: Add Arrow entered source selection; no completed arrow verified. Opens the cited page.Curved mechanism arrowsAdd Arrow entered source selection; no completed arrow verified.github.com
• Yes, according to the manual: Reaction JSON preserves steps; RXN V2000 supports one step. Opens the cited page.Machine-readable reactionsReaction JSON preserves steps; RXN V2000 supports one step.github.com
• Yes, according to the manual: Atom-map numbers can be assigned manually. Opens the cited page.Atom mappingAtom-map numbers can be assigned manually.github.com
• Not establishedOrbitals and symbols

Figures and layout

• Partly: Plain text annotations only; fixed font without subscript/superscript controls. Opens the cited page.Rich text captionsPlain text annotations only; fixed font without subscript/superscript controls.github.com
• Partly: Text, arrows and brackets; no general shape or curve tools. Opens the cited page.Shapes, brackets and curvesText, arrows and brackets; no general shape or curve tools.github.com
• Partly: Aligns/distributes selected atoms; no whole-object layout. Opens the cited page.Align and distributeAligns/distributes selected atoms; no whole-object layout.github.com
• No: Group controls are inactive; imported groups have limited editing. Opens the cited page.Group and ungroupGroup controls are inactive; imported groups have limited editing.github.com
• Yes, according to the manual: Clean Up Structure command is available. Opens the cited page.2D structure cleanupClean Up Structure command is available.github.com
• Not establishedJournal drawing styles
• Not establishedReusable custom styles
• No: Colors controls are inactive. Opens the cited page.Color controlColors controls are inactive.github.com
• Partly: Orange atom selection backgrounds only; exports omit them. Opens the cited page.Color highlightingOrange atom selection backgrounds only; exports omit them.github.com
• Partly: CDXML multipage interchange; page-layout editing is not established. Opens the cited page.Page layout and multipageCDXML multipage interchange; page-layout editing is not established.github.com
• Not establishedImported pictures
• Not establishedTLC plates and tables

Chemistry intelligence

• Yes, according to the manual: Validates chemical valence and reports structure errors. Opens the cited page.Structure checkingValidates chemical valence and reports structure errors.github.com
• Yes, according to the manual: Computes R/S and E/Z; ambiguous assignments are omitted. Opens the cited page.R/S and E/Z labelsComputes R/S and E/Z; ambiguous assignments are omitted.github.com
• Yes, tested by running it: Caffeine showed C8H10N4O2 and 194.19. Opens the cited page.Formula and massCaffeine showed C8H10N4O2 and 194.19.github.com
• Yes, tested by running it: Property panel displayed MW, LogP, and ring count. Opens the cited page.Property estimatesProperty panel displayed MW, LogP, and ring count.github.com
• Yes, according to the manual: Desktop ChemSpider lookup requires configured API access and network. Opens the cited page.Name to structureDesktop ChemSpider lookup requires configured API access and network.github.com
• Partly: Research identifiers showed an empty IUPAC Name field. Opens the cited page.Structure to nameResearch identifiers showed an empty IUPAC Name field.github.com
• No: Prediction is explicitly unimplemented; peak import and manual annotation exist. Opens the cited page.NMR predictionPrediction is explicitly unimplemented; peak import and manual annotation exist.github.com
• Yes, according to the manual: Supports atom lists, wildcards, Markush and R-group query data. Opens the cited page.R-groups and query structuresSupports atom lists, wildcards, Markush and R-group query data.github.com
• Yes, according to the manual: Semantic repeat units support bounded two-attachment expansion. Opens the cited page.Polymers and repeat unitsSemantic repeat units support bounded two-attachment expansion.github.com
• Partly: Nucleic-acid residue metadata editing; no sequence-to-structure builder established. Opens the cited page.Peptides and nucleic acidsNucleic-acid residue metadata editing; no sequence-to-structure builder established.github.com
• Not establishedImage to structure
• Yes, according to the manual: Fetches importable SMILES; approximate InChIKeys can miss PubChem matches. Opens the cited page.Online structure lookupFetches importable SMILES; approximate InChIKeys can miss PubChem matches.github.com
• Partly: Generated cholesterol model; viewport clipped it severely. Opens the screenshot.3D model viewGenerated cholesterol model; viewport clipped it severely.github.com
• Not establishedCrystal structures

Files and exchange

• Partly: Reads/writes a subset; advanced presentation is not preserved losslessly. Opens the cited page.CDXML import and exportReads/writes a subset; advanced presentation is not preserved losslessly.github.com
• Not establishedCDX import and export
• Partly: MOL export worked; Open dialog disabled fixture MOL and SDF. Opens the screenshot.MOL and SDFMOL export worked; Open dialog disabled fixture MOL and SDF.github.com
• Partly: Paste and export worked; cholesterol export lost stereochemistry. Opens the cited page.SMILESPaste and export worked; cholesterol export lost stereochemistry.github.com
• Partly: Research panel displayed explicitly approximate InChI and derived InChIKey. Opens the cited page.InChIResearch panel displayed explicitly approximate InChI and derived InChIKey.github.com
• Yes, according to the manual: One-step RXN V2000; agents and coefficients require loss confirmation. Opens the cited page.RXN filesOne-step RXN V2000; agents and coefficients require loss confirmation.github.com
• Yes, tested by running it: SVG downloaded for caffeine, paclitaxel, and cholesterol. Opens the screenshot.SVG exportSVG downloaded for caffeine, paclitaxel, and cholesterol.github.com
• No: Export shortcut referred to unavailable File menu; no PDF control. Opens the cited page.PDF exportExport shortcut referred to unavailable File menu; no PDF control.github.com
• Yes, tested by running it: PNG downloaded for caffeine. Opens the screenshot.High-resolution PNGPNG downloaded for caffeine.github.com
• No: Clipboard accepts text/plain only; native ChemDraw objects are unsupported. Opens the cited page.Paste to and from ChemDrawClipboard accepts text/plain only; native ChemDraw objects are unsupported.github.com
• Not establishedEditable in Word or PowerPoint
• Not establishedWindows Office OLE

APIs and automation

• Not establishedPython API
• Yes, according to the manual: Documented TypeScript/WASM bridge and public Web Component package. Opens the cited page.JavaScript or TypeScript APIDocumented TypeScript/WASM bridge and public Web Component package.github.com
• Not establishedCommand-line tool
• Not establishedAI agent control
• No: Chat only answers keyword queries; cannot propose or edit drawings. Opens the cited page.Built-in AI assistantChat only answers keyword queries; cannot propose or edit drawings.github.com

Embedding and extension

• Yes, according to the manual: In-process extension registration only; third-party bundle loading is disabled. Opens the cited page.PluginsIn-process extension registration only; third-party bundle loading is disabled.github.com
• Partly: Unpublished source package; basic editing only; host supplies controls. Opens the cited page.Embed in your own appUnpublished source package; basic editing only; host supplies controls.github.com