Ketcher

• Tested by running it
• Seen in the app
• The manual says yes
• Partly, with the reason shown
• Not supported
• Not established, which is not the same as no

Select a mark for its proof. A filled mark opens our screenshot, or the manual if the check left nothing to picture. A ring opens the manual.

Drawing structures

• Yes, tested by running it: Drew single, double and triple bonds. Opens the screenshot.Single, double and triple bondsDrew single, double and triple bonds.github.com
• Yes, tested by running it: Drew solid, hashed and wavy bonds. Opens the screenshot.Wedge, hash and wavy bondsDrew solid, hashed and wavy bonds.github.com
• Yes, according to the manual: Dative and hydrogen bonds are available. Opens the cited page.Dative, hydrogen and quadruple bondsDative and hydrogen bonds are available.github.com
• Not establishedChoose double-bond side
• Yes, tested by running it: Placed benzene and cyclohexane rings. Opens the screenshot.Ring toolsPlaced benzene and cyclohexane rings.github.com
• Yes, according to the manual: Chair conformation templates are included. Opens the cited page.Chair and Haworth ringsChair conformation templates are included.github.com
• Yes, according to the manual: Dragging sets the number of zigzag carbon-chain bonds. Opens the cited page.Chain toolDragging sets the number of zigzag carbon-chain bonds.github.com
• Yes, tested by running it: Placed L-alanine from the structure library. Opens the screenshot.Template libraryPlaced L-alanine from the structure library.github.com
• Yes, according to the manual: Save to Templates creates reusable user templates. Opens the cited page.Save your own templatesSave to Templates creates reusable user templates.github.com
• Yes, according to the manual: Functional groups expand, contract and retain underlying chemistry. Opens the cited page.Group abbreviationsFunctional groups expand, contract and retain underlying chemistry.github.com
• Yes, according to the manual: Element labels, aliases, charge and isotope properties are editable. Opens the cited page.Charges, isotopes and atom labelsElement labels, aliases, charge and isotope properties are editable.github.com
• Yes, according to the manual: Mono- and diradical states are available. Opens the cited page.Radicals and lone pairsMono- and diradical states are available.github.com
• Yes, according to the manual. Opens the cited page.Keyboard drawingrc.test.lifescience.opensource.epam.com
• Partly: Lasso and fragment selection visible; transforms not verified. Opens the cited page.Lasso select and transformsLasso and fragment selection visible; transforms not verified.
• Not establishedTilt drawings in perspective

Reactions and mechanisms

• Yes, tested by running it: Drew forward and equilibrium arrows. Opens the screenshot.Reaction arrowsDrew forward and equilibrium arrows.github.com
• Yes, tested by running it: Drew an elliptical half-headed arrow. Opens the screenshot.Curved mechanism arrowsDrew an elliptical half-headed arrow.github.com
• Yes, according to the manual: RXN export stores reactants and products. Opens the cited page.Machine-readable reactionsRXN export stores reactants and products.github.com
• Yes, according to the manual: Manual mapping, automatic mapping and unmapping tools. Opens the cited page.Atom mappingManual mapping, automatic mapping and unmapping tools.github.com
• Yes, according to the manual: Special-symbol palette includes Greek letters, temperature and Angstrom symbols. Opens the cited page.Orbitals and symbolsSpecial-symbol palette includes Greek letters, temperature and Angstrom symbols.github.com

Figures and layout

• Yes, according to the manual: Styled captions support subscripts and superscripts; font settings are global. Opens the cited page.Rich text captionsStyled captions support subscripts and superscripts; font settings are global.github.com
• Yes, according to the manual: Ellipse, rectangle and line tools; S-groups provide brackets. Opens the cited page.Shapes, brackets and curvesEllipse, rectangle and line tools; S-groups provide brackets.github.com
• Not establishedAlign and distribute
• Not establishedGroup and ungroup
• Yes, according to the manual: Clean Up makes bond lengths and angles uniform. Opens the cited page.2D structure cleanupClean Up makes bond lengths and angles uniform.github.com
• Yes, according to the manual: Built-in ACS settings. Opens the cited page.Journal drawing stylesBuilt-in ACS settings.github.com
• Yes, according to the manual: Bond and font settings persist in browser storage. Opens the cited page.Reusable custom stylesBond and font settings persist in browser storage.github.com
• Yes, according to the manual: Selected atoms and bonds can receive individual highlight colors. Opens the cited page.Color controlSelected atoms and bonds can receive individual highlight colors.github.com
• Yes, according to the manual: Eight highlight colors add backgrounds behind atoms and bonds. Opens the cited page.Color highlightingEight highlight colors add backgrounds behind atoms and bonds.github.com
• Not establishedPage layout and multipage
• Yes, according to the manual: PNG and SVG images can be placed on the canvas. Opens the cited page.Imported picturesPNG and SVG images can be placed on the canvas.github.com
• Not establishedTLC plates and tables

Chemistry intelligence

• Yes, according to the manual: Invalid valence is underlined in red. Opens the cited page.Structure checkingInvalid valence is underlined in red.github.com
• Yes, according to the manual: Calculate CIP assigns R/S, r/s and E/Z descriptors. Opens the cited page.R/S and E/Z labelsCalculate CIP assigns R/S, r/s and E/Z descriptors.github.com
• Yes, tested by running it: Caffeine: C8H10N4O2; molecular weight 194.194. Opens the screenshot.Formula and massCaffeine: C8H10N4O2; molecular weight 194.194.github.com
• Not establishedProperty estimates
• No: Pasting caffeine as a name produced a conversion error. Opens the cited page.Name to structurePasting caffeine as a name produced a conversion error.
• No: No naming command found in inspected controls. Opens the cited page.Structure to nameNo naming command found in inspected controls.
• Not establishedNMR prediction
• Yes, according to the manual: R-groups, atom lists, attachment points and R-group logic. Opens the cited page.R-groups and query structuresR-groups, atom lists, attachment points and R-group logic.github.com
• Yes, according to the manual: SRU and copolymer S-groups encode repeating units and connectivity. Opens the cited page.Polymers and repeat unitsSRU and copolymer S-groups encode repeating units and connectivity.github.com
• Yes, according to the manual: Monomer library, sequence editing, FASTA and HELM. Opens the cited page.Peptides and nucleic acidsMonomer library, sequence editing, FASTA and HELM.github.com
• Yes, according to the manual: Requires remote Imago service; unavailable in standalone mode. Opens the cited page.Image to structureRequires remote Imago service; unavailable in standalone mode.github.com
• Not establishedOnline structure lookup
• Yes, tested by running it: Rotated SDF coordinates; SMILES import remained planar. Opens the screenshot.3D model viewRotated SDF coordinates; SMILES import remained planar.github.com
• Not establishedCrystal structures

Files and exchange

• Yes, tested by running it: Exported CDXML and reopened it. Opens the cited page.CDXML import and exportExported CDXML and reopened it.github.com
• Yes, according to the manual. Opens the cited page.CDX import and exportgithub.com
• Yes, tested by running it: Opened MOL and SDF; exported MOL. Opens the screenshot.MOL and SDFOpened MOL and SDF; exported MOL.github.com
• Yes, tested by running it: Imported and exported SMILES. Opens the cited page.SMILESImported and exported SMILES.github.com
• Yes, according to the manual. Opens the cited page.InChIgithub.com
• Yes, according to the manual: RXN V2000 and V3000. Opens the cited page.RXN filesRXN V2000 and V3000.github.com
• Yes, tested by running it: Exported SVG for all three fixtures. Opens the cited page.SVG exportExported SVG for all three fixtures.github.com
• No: No PDF option in Save Structure format list. Opens the cited page.PDF exportNo PDF option in Save Structure format list.
• Partly: Default PNG exported; high-resolution option not verified. Opens the cited page.High-resolution PNGDefault PNG exported; high-resolution option not verified.github.com
• Partly: MOL-text exchange; direct ChemDraw OLE clipboard pasting is unsupported. Opens the cited page.Paste to and from ChemDrawMOL-text exchange; direct ChemDraw OLE clipboard pasting is unsupported.github.com
• Not establishedEditable in Word or PowerPoint
• Not establishedWindows Office OLE

APIs and automation

• Not establishedPython API
• Yes, according to the manual. Opens the cited page.JavaScript or TypeScript APIgithub.com
• Not establishedCommand-line tool
• Not establishedAI agent control
• Not establishedBuilt-in AI assistant

Embedding and extension

• Yes, according to the manual: Custom toolbar buttons invoke application-defined handlers. Opens the cited page.PluginsCustom toolbar buttons invoke application-defined handlers.github.com
• Yes, according to the manual: Mount React Editor with a structServiceProvider; or iframe standalone release. Opens the cited page.Embed in your own appMount React Editor with a structServiceProvider; or iframe standalone release.github.com