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ChemDoodle 2D
Desktop software for drawing chemical structures, reactions, and publication figures.
Paid. 58 of 65 checklist features confirmed.
Official demo
Main canvas
Paid, checked from the manual
Paid, checked from the manual
Default drawings
Paid, checked from the manual
Caffeine
Paid, checked from the manual
Paclitaxel
Paid, checked from the manual
Cholesterol in 3D
Facts
- Latest version
- 12.12.1
- Runs on
- macOS, Windows, Linux
- License
- Proprietary paid license; 14-day evaluation trial.
- Price
- 2026-11-05: USD $29/month, $199/year, or $999 lifetime; suite license, plus tax.
- Plans
- iChemLabs Suite: 2026-11-06: US$29/month, US$199/year, or US$999 lifetime; +tax.
- Relies on
- OPSIN. OPSIN confirmed in vendor changelog; canvas provenance unestablished.
- Chemistry from
- ChemDoodle cheminformatics engine and OPSIN
- Main language
- Java
- Other languages
- Not established
- Renderer
- Original: ChemDoodle Java graphics library
- Third-party licenses
- Linux bundle: LGPL libraries; LibrePDF MPL-1.1/LGPL; EPL-2.0; vecmath/Temurin GPL-2.0 with Classpath exceptions; Apache/BSD/MIT; FreeType FTL/GPL-2.0; MPL-2.0 Public Suffix List data. jsr-275 license unspecified.
- Sold only as part of the iChemLabs suite.
- Internet access is required for activation.
- Office round-trip editing depends on operating system and application compatibility.
Features
- Tested by running it
- Seen in the app
- The manual says yes
- Partly, with the reason shown
- Not supported
- Not established, which is not the same as no
Select a mark for its proof. A filled mark opens our screenshot, or the manual if the check left nothing to picture. A ring opens the manual.
Drawing structures
- Yes, according to the manual. Opens the cited page.Single, double and triple bondsichemlabs.com
- Yes, according to the manual. Opens the cited page.Wedge, hash and wavy bondsichemlabs.com
- Yes, according to the manual: Dative, hydrogen, and zero-order bonds. Opens the cited page.Dative, hydrogen and quadruple bondsDative, hydrogen, and zero-order bonds.ichemlabs.com
- Yes, according to the manual: Flip asymmetric bonds; symmetry settings center them. Opens the cited page.Choose double-bond sideFlip asymmetric bonds; symmetry settings center them.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Ring toolsichemlabs.com
- Yes, according to the manual. Opens the cited page.Chair and Haworth ringsichemlabs.com
- Yes, according to the manual. Opens the cited page.Chain toolichemlabs.com
- Yes, according to the manual. Opens the cited page.Template libraryichemlabs.com
- Yes, according to the manual. Opens the cited page.Save your own templatesichemlabs.com
- Yes, according to the manual. Opens the cited page.Group abbreviationsichemlabs.com
- Yes, according to the manual. Opens the cited page.Charges, isotopes and atom labelsichemlabs.com
- Yes, according to the manual. Opens the cited page.Radicals and lone pairsichemlabs.com
- Yes, according to the manual. Opens the cited page.Keyboard drawingichemlabs.com
- Yes, according to the manual. Opens the cited page.Lasso select and transformsichemlabs.com
- Yes, according to the manual. Opens the cited page.Tilt drawings in perspectiveichemlabs.com
Reactions and mechanisms
- Yes, according to the manual. Opens the cited page.Reaction arrowsichemlabs.com
- Yes, according to the manual. Opens the cited page.Curved mechanism arrowsichemlabs.com
- Yes, according to the manual: RXN and reaction SMILES retain reactants and products. Opens the cited page.Machine-readable reactionsRXN and reaction SMILES retain reactants and products.ichemlabs.com
- Yes, according to the manual: Manual mapping; stored in RXN, SMILES, CDX, and CDXML. Opens the cited page.Atom mappingManual mapping; stored in RXN, SMILES, CDX, and CDXML.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Orbitals and symbolsichemlabs.com
Figures and layout
- Yes, according to the manual. Opens the cited page.Rich text captionsichemlabs.com
- Yes, according to the manual. Opens the cited page.Shapes, brackets and curvesichemlabs.com
- Yes, according to the manual. Opens the cited page.Align and distributeichemlabs.com
- Yes, according to the manual. Opens the cited page.Group and ungroupichemlabs.com
- Yes, according to the manual. Opens the cited page.2D structure cleanupichemlabs.com
- Yes, according to the manual: ACS, RSC, and Nature presets. Opens the cited page.Journal drawing stylesACS, RSC, and Nature presets.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Reusable custom stylesichemlabs.com
- Yes, according to the manual. Opens the cited page.Color controlichemlabs.com
- Yes, according to the manual: Filled highlights around selected atoms and bonds. Opens the cited page.Color highlightingFilled highlights around selected atoms and bonds.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Page layout and multipageichemlabs.com
- Yes, according to the manual. Opens the cited page.Imported picturesichemlabs.com
- Yes, according to the manual. Opens the cited page.TLC plates and tablesichemlabs.com
Chemistry intelligence
- Yes, according to the manual. Opens the cited page.Structure checkingichemlabs.com
- Yes, according to the manual. Opens the cited page.R/S and E/Z labelsichemlabs.com
- Yes, according to the manual. Opens the cited page.Formula and massichemlabs.com
- Yes, according to the manual: Includes logP and TPSA estimates. Opens the cited page.Property estimatesIncludes logP and TPSA estimates.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Name to structureichemlabs.com
- Yes, according to the manual. Opens the cited page.Structure to nameichemlabs.com
- Yes, according to the manual: Predicts proton and carbon-13 shifts. Opens the cited page.NMR predictionPredicts proton and carbon-13 shifts.ichemlabs.com
- Not establishedR-groups and query structures
- Yes, according to the manual: Integer repeat counts expand into all-atom structures. Opens the cited page.Polymers and repeat unitsInteger repeat counts expand into all-atom structures.ichemlabs.com
- Yes, according to the manual: Amino-acid sequence construction. Opens the cited page.Peptides and nucleic acidsAmino-acid sequence construction.ichemlabs.com
- Yes, according to the manual. Opens the cited page.Image to structureichemlabs.com
- Yes, according to the manual: Retrieves structures from PubChem, ChemSpider, and ChemExper. Opens the cited page.Online structure lookupRetrieves structures from PubChem, ChemSpider, and ChemExper.ichemlabs.com
- Yes, according to the manual: Rotatable orthographic models; advanced graphics use companion ChemDoodle 3D. Opens the cited page.3D model viewRotatable orthographic models; advanced graphics use companion ChemDoodle 3D.ichemlabs.com
- Yes, according to the manual: CIF import; vendor claim. Opens the cited page.Crystal structuresCIF import; vendor claim.ichemlabs.com
Files and exchange
- Yes, according to the manual. Opens the cited page.CDXML import and exportichemlabs.com
- Yes, according to the manual. Opens the cited page.CDX import and exportichemlabs.com
- Yes, according to the manual. Opens the cited page.MOL and SDFichemlabs.com
- Yes, according to the manual. Opens the cited page.SMILESichemlabs.com
- Yes, according to the manual. Opens the cited page.InChIichemlabs.com
- Yes, according to the manual. Opens the cited page.RXN filesichemlabs.com
- Yes, according to the manual. Opens the cited page.SVG exportichemlabs.com
- Yes, according to the manual. Opens the cited page.PDF exportichemlabs.com
- Yes, according to the manual: PNG resolution is configurable; default is 300 dpi. Opens the cited page.High-resolution PNGPNG resolution is configurable; default is 300 dpi.ichemlabs.com
- Yes, according to the manual: Chemical clipboard formats; compatibility depends on platform. Opens the cited page.Paste to and from ChemDrawChemical clipboard formats; compatibility depends on platform.ichemlabs.com
- Yes, according to the manual: Windows OLE; macOS copy-and-paste round-trip workflow. Opens the cited page.Editable in Word or PowerPointWindows OLE; macOS copy-and-paste round-trip workflow.ichemlabs.com
- Partly: Windows OLE; repeated Word double-click edits require delete/undo workaround. Opens the cited page.Windows Office OLEWindows OLE; repeated Word double-click edits require delete/undo workaround.ichemlabs.com
APIs and automation
- Not establishedPython API
- Not establishedJavaScript or TypeScript API
- Not establishedCommand-line tool
- Not establishedAI agent control
- Not establishedBuilt-in AI assistant
Embedding and extension
- Not establishedPlugins
- Partly: Separate Web Components product; GPLv3 or proprietary license. Opens the cited page.Embed in your own appSeparate Web Components product; GPLv3 or proprietary licenseweb.chemdoodle.com